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Excellent summary Göte. I would just add one thing for those with too much (computer) time on their hands. As the optimum aperture for maximum sharpness is in the range f8-f11 (because the lens maunfacturers design them that way), then if this isn't going to give you front-to-back sharpness of the subject you can take a series of images with slightly different points of focus and merge them in the computer - a procedure known as focus stacking. There are even relatively inexpensive progammes that will preform the job for you whilst you make a cup of coffee or go and do some light weeding.
I recall reading a good post by Göte in which he showed the effect of diffraction at small aperture. Alas I've failed to find it again.Attached are two sets of three photos taken at f2.8, f11 and f32, the first set show that as the aperture decreases depth of field increases. The second set show sharpness peaks in the middle.Photos are of a 1mm laser printed grid, taken with Minolta 50mm f2.8 macro lens at closest focusing distance.
I cannot trace that post you mention from Göte ... might it have been in the "old" Forum?
I assume that such a program will also re-center the pictures since ther will be inevitable movement between each exposure.